How is knowing the defense going to help a running back? If Ware is in the game, he's going to run into the hole the coaches tell him to or catch the ball where the coaches tell him to. From there his individual talent and the talents of his teammates will decide if it is a successful play or not. Knowing the defense doesn't help him.
In the game, no. But game planning, you bet that he knows some of their schemes, tendencies, and weaknesses even. He's helping the team as a whole. But yes, his individual talent is his own. His experiences against that line will be a plus though. I know for a fact he's been sent in to slow down JPP or another lineman.