Vick will start in place of an injured Kevin Kolb this week against the Detroit Lions. I'm expecting Vick to play like he did with the Falcons. The Lions pass defense hasn't improved very much from last season, which means Vick's strong arm should be showcased in this matchup. Vick threw for 175 passing yards and a touchdown, along with 103 rushing yards against a stout Packers defense. Vick will look like the Vick of old this week against the Lions, and I believe he will be a top 10 quarterback this week.
QB - Joe Flacco
"Joe Cool" had a tough opponent to start the 2010 season, when the Ravens played the New York Jets. He still managed to pass for 248 yards, which says a lot to me. Flacco showed that he can do more than just manage a game. Running back Ray Rice couldn't get anything on the ground, but Flacco picked up the slack. Flacco goes up against a Cincinatti Bengals defense that had a shaky outing against the New England Patriots last week. Brady finished with 258 yards passing, which makes me salivate at what Flacco can do after he threw for nearly that much against the Jets.
RB - LeSean McCoy
McCoy exceded my expectations last week against a very good Packers defense. The Eagles running back finished with 82 total yards, and found the endzone once. This week McCoy gets the Detriot Lions. Last week the Lions gave up 150 receiving yards to Bears' running back Matt Forte. The Eagles love to throw to the running back out of the backfield, so McCoy could be in for a very productive week. I see him as a high RB2 option for week two.
RB - Brandon Jackson
Ryan Grant owners cringed when they saw their man go down last Sunday against the Packers. Hopefully in between tears, they tried to pickup his backup Brandon Jackson. Jackson is a more than servicable play against a putrid Buffalo Bills run defense. The Bills surrendered 132 rushing yards to the Dolphins in week one. I expect Jackson to get between 18-25 carries, and finish around the century-mark in rushing yards against the Bills.
WR - Santana Moss
Moss caught six passes for 77 yards against a very solid Dallas Cowboys defense. The Houston Texans might be coming off a win, but their pass defense didn't play like a winner against the Colts. Three different receivers caught a touchdown from Peyton Manning, while Austin Collie totale 163 receiving yards on 11 catches. This seems to be a great matchup for the veteran Redskins receiver. Moss still has some good fantasy games left in his tank, and I think you will see one of those against the Texans. I predict Moss will total good enough numbers to be considered a WR2.
WR - Robert Meachem
The New Orleans Saints have lots of weapons on offense. It will be hard for the San Francisco defense to gameplan for all of them. I think the guy that the 49ers might forget about will be Robert Meachem. The Saints receiver dropped a sure touchdown last week against the Vikings, which would have given him 7 more fantasy points to add to the three he had. The 49ers had a rough outing against the Seattle Seahawks, where quarterback Matt Hasselback threw a pair of touchdowns. Play Meachem as a sneaky WR3 this week.
DEF - Falcons
I like the Falcons defense this week against the Arizona Cardinals. Derek Anderson and the Cardinals offense sputtered in their first game against the Rams. I'm not so sure that all the kinks are will be worked out by week two. The Falcons have a much better defense than the Rams did in week one, so I expect about 9-12 fantasy points coming from the Falcons this week.