There are so many stupid things posted here by MAGA, but one that really stands out is the full display of ignorance on the vaccine that you see from Runole, Buggsy, Kermit, etc. Its not that they should be scientist (lolol wed be truly f-d if thats what we needed), but how about JUST READ A BIT?
If you did - and maybe if you started with Operation Warp Speed because of its connection to Trump -- youd probably see how freaking stupid you all look . . especially bashing Fauci of all people.
You could read something like this from Science News, easily found with Google:
"How COVID-19 vaccines were made so quickly without cutting corners"
"The spread of the virus and the public’s attention to science helped to shorten the timeline"
Its actually an incredible story of AMERICAN EXCEPTIONALISM .. in so many different ways . . SCIENCE, volunteerism, government, leadership . . much of it happening quietly, behind the scenes . . as you choke down Bud Lights watching Tucker or listening o LImbaugh (it goes back that far and more)
BECAUSE NONE OF YOIU WEILL BOTHER . . the COCOON is more important, here is the very short version. NOTICE HOW MUCH OF THE WORK on the CV19 vaccine comes from OTHER PRIOR WORK. That's called . . . SCIENCE
"Driven by a global urgency and underpinned by decades of prior work on vaccine technology, vaccine developers found a way to chop not just days or months, but years off the timeline (SN: 2/21/20). What was jettisoned was not the science, or the safety tests, but rather the wait time baked into the development process — waiting for results and waiting for regulatory approvals (SN: 7/10/20)."
1. OWING TO PRIOR REASEARCH, the virus was IDENTIFIED very very quickly
The Clock was ticking right from the start -- while Trump downplayed itBUT .. science to the rescue:
"It began with deciphering the exact genetic makeup of SARS-CoV-2, the virus that causes COVID-19 (SN: 12/11/20). By early January 2020, that genetic blueprint was in hand and the first vaccines to test were ready just a few weeks later."
JANUARY 2020. The Trump "I got bad news" press conference was March?
If you read about it a big rason this hapened so quickly: DECADES OF GENOME REASEARCH 1990-2003
2. Spike Proteins Developed VERY QUICKLY because of the genetic identification and COV1 research
and this is why you see mention of Cov-1 in the recent beatdown of Runole and Buggsy and their stupid "the vaccine doesnt work" claims:
"Most crucially, researchers now had the genetic instructions for making the spike proteins that the virus uses to break into cells — a key ingredient for making the vaccines. Jutting out from the virus’ surface, these spike proteins make an easy target for the immune system to recognize. Researchers knew to zero in on those proteins thanks to decades of work studying coronaviruses, including two that have caused other outbreaks of human diseases — SARS and MERS.
3. BUT YOU STILL HAVE TO DELIVBER THE PROTEINS -- PRIOR SCIENCE AGAIN
Fauci to the rescue, @JBear
"Scientists had already built these rapid, genetically based templates largely because of the ongoing battle against HIV, says Tom Denny, Chief Operating Officer of the Duke Human Vaccine Institute in Durham, N.C.
“In the last 10 to 15 years, there’ve been major teams around the world … trying to understand what needed to occur to make a protective HIV vaccine,” Denny says. Those efforts have “helped us in our battle with this current pandemic.”
That ^^^^ is FAUCI'S Life's work . . . something that was very controversial when he started it (in part due to the homophobia on display here daily)
"Denny calls it “plug-and-play” vaccine manufacturing. Decades of trying to attack HIV has created a library of safe weapons to use quickly against any new would-be viral marauders. “We got lucky,” Denny says, that the developed platforms have worked so well for this new deadly virus.
One of the templates directly carries a nonfunctional, partial strand of viral mRNA to cells in the body, delivering instructions for those cells to create copies of the protein that the immune system recognizes as foreign. That’s what’s used in the Pfizer-BioNTech and Moderna shots.
4. mRNA plays a HUGE role IN THE SPEED and that comes from PRIOR Scientific RESEARCH and TESTING
"Years of data from monitoring patients who had been injected with these RNA fragments wrapped in lipid nanoparticles shows they’re safe, says Sascha Tuchman, a hematologist-oncologist at the University of North Carolina at Chapel Hill who oversaw a site for the Phase III patisiran trials. Patients who receive a dose of patisiran have a lower risk of side effects than those who got injections with placebo saline. And when it comes to long-term negative consequences from RNA and lipid nanoparticles, Tuchman says, “we haven’t seen anything additional in terms of the safety that would indicate that there is some reason to be concerned.”
Six years after the first shots began being tested, the FDA approved patisiran, a little faster than standard pace for new treatments. That makes it a good comparison to show where the COVID-19 vaccines were able to cut time, not counting the decades of research of development that got us to this point. So let’s start the clock."
5. JUST LIKE IN WARTIME -- PEOPLE VOLUNTEER
"After the first syringefuls of prospective COVID-19 vaccine emerged from the “plug-and-play” mRNA labs, years were removed from the timeline by cutting out the long stretches of pure waiting that are built into most human testing. Driven by the urgency of the pandemic, nearly half a million people in America alone had offered up their deltoids for the cause through the COVID-19 Prevention Network in a matter of months, in many cases even before the first public inklings of success, according to the American Medical Association.
For instance, it took just under 16 weeks to recruit and enroll more than 43,000 volunteers for the final phases of testing Pfizer’s vaccine. When volunteer recruitment began for clinical trials of the rabies mRNA vaccine in 2013, it took 813 days to get 101 participants enrolled. Based on this comparison, that’s roughly 730 days — nearly two years — saved in recruiting alone."
6. The TIE-IN TO RUNOLE/BUGGSY CLAIM THE VACCINE DOES NOT WORK
"Another, more dismal factor contributed to the scientific speed: How fast the virus spread.
Scientists can begin to calculate a vaccine’s efficacy when a sufficient number of people in the group that got a placebo rather than a vaccine have gotten infected naturally (SN: 10/4/20). If an outbreak peters out, it takes longer to reach that threshold. That’s true too if a virus naturally spreads more slowly — say a virus like HIV, herpes or human papillomavirus, or HPV, which are transmitted primarily through sex. In contrast, just breathing or talking can spread SARS-CoV-2 — and everybody does that (SN: 4/2/20).
SO THE FAST SPREAD OF THE VIRUS HELPED GET EFFICACY INFORMATION QUICKLY (ie scientist do not KNOW how much immunity a vaccine will confer UNTIL the testing is completed)
"The Pfizer Phase II/III coronavirus trial, in contrast, got initial efficacy results for the first of its two doses in just 105 days, when it hit a nearly 2.4 percent infection rate in the placebo group. That’s 424 days faster than HPV. Why? Because just months into the pandemic, SARS-CoV-2 was infecting hundreds of thousands of people per day globally."
7. THE FDA HAS NO CHOICE BUT TO MOVE THE VACCINE TO FRONT OF LINES
"There was also waiting time recouped from the U.S. Food and Drug Administration’s review process. Typically, it takes the FDA 10 months to review a new drug.
However, with the COVID-19 death toll rising, the FDA rushed all coronavirus vaccines to the front of the review lines. The Pfizer vaccine got reviewed and authorized for emergency use only 21 days after submission and the Moderna vaccine in just 19 days (SN: 12/11/20; SN: 12/18/20). Compared with a more typical 10-month wait time, that’s about another 283 days saved.
In total, that’s 1,437 days, or 3.9 years, cut off the normal timeline for a new vaccine."
8. OPERATION WARP SPEED GIVES AMERICAN $ TO TAKE AWAY RISK FOR PRIVATE COMPAINES
American money and American wealth pushes manufacturers to start manufacturing an unproven vaccine. This is the Trump program and he deserves credit
"In a final jolt of speed, some pharmaceutical companies, bolstered by big vaccine contracts and research cash from the U.S. government’s Operation Warp Speed, were also churning out doses during clinical trials in the hopes that the vaccines would work. Once the companies had emergency use authorization in hand, they were ready to ship doses immediately."
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This should be an American success story . . . but its not.
It's not because there is SO MUCH DISINFORMATION and its even spread by political people (like Rand Paul) who are looking out for their own wallets and power OVER the people they represent
