Ideal playing weight for Vea

So I was reading recently about Bradley Culpepper and how he has lost over 100 pounds since retiring. He speaks out about the dangers of NFL players being so heavy today and it hot me thinking about what the ideal playing weight for Vea to be. He was listed at 347 but I can't help but think he'd be more productive, healthy, and have better 4th quarter endurance if he dropped to about 320
I guess it depends on his BMI. In his picture at the facility I didn't think he looked fat, just big. Anyways, just wondering what you guys think.