https://neurosciencenews.com/brain-organization-consciousness-15132/
https://www.frontiersin.org/articles/10.3389/fnins.2019.01106/full
"Using available neural recordings from human participants during wakefulness, sleep, coma and seizures — each considered a brain “macrostate” — the team found that entropy during consciousness was higher than that during unconscious states.
“To maintain healthy brain states then is not about the total amount of energy in the brain […] but rather in how the energy is organized,”
"As a result, the brain has lower entropy and so reduced ability to form variable brain activity patterns. That is, it has fewer microstates, resulting in fewer configurations of interacting neural networks, which deprives the brain of its usual ability to quickly and flexibly adapt to the outside world. In some cases, consciousness also crumbles."