Trump would also effectively "lose" if he won re-lection, but lost control of the Senate. Is there a chance the Dems take control of the Senate?
In a Trump win scenario, they would need to gain FIVE seats (assuming they lose AL):
Colorado: Dem Hickenlooper is +8 to +10 in most polls
Arizona: Dem Kelly is +6 to +12 (and McSally was just embarrassed by Trump)
Maine: Dem Gideon is +2 to +3 over Collins
North Carolina: toss up right now, although many pols have Dem Cunningham leading
Iowa: toss up right now, but Ernst just had a terrible debate performance
But both GA seats are also in play, as is SC (incredibly) and Montana
(It is almost impossible to displace a sitting Senator because they have so much money and control, including millions from McConnell's and Schumer's Senate fund (this is why they lockstep all the time and really one of the biggest problems in the Republic)